Pharmacogenetics and bipolar disorder
نویسندگان
چکیده
منابع مشابه
Towards the clinical implementation of pharmacogenetics in bipolar disorder
BACKGROUND Bipolar disorder (BD) is a psychiatric illness defined by pathological alterations between the mood states of mania and depression, causing disability, imposing healthcare costs and elevating the risk of suicide. Although effective treatments for BD exist, variability in outcomes leads to a large number of treatment failures, typically followed by a trial and error process of medicat...
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We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. Despite their widespr...
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INTRODUCTION In the ongoing quest for improved diagnostic markers of bipolar illness, the focus of research has gradually shifted to examining the onset of mood difficulties early in life and investigating the potential corollaries of such early onset such as cognitive impairment, disruption of social and emotional functioning, and constriction of quality of life. This article considers the dis...
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Introduction: The purpose of this study was to investigate and compare personality dimensions of temperament and character in patients with borderline personality and bipolar II disorders in order to evaluate the hypothesis of “belonging of borderline personality disorder in moods disturbance spectrum.” Materials and Methods: 43 patients with borderline personality disorder, 47 patients with bi...
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ژورنال
عنوان ژورنال: The Pharmacogenomics Journal
سال: 2004
ISSN: 1470-269X,1473-1150
DOI: 10.1038/sj.tpj.6500245